Preparation
Your doctor will want to know about your health status especially if you have any allergies, other significant health problems such as heart disease, lung disease, diabetes mellitus, etc. If there is a possibility of fine needle aspiration (FNA), the doctor may want to check your blood for proper clotting. It is important to inform your doctor of any family history of bleeding problems or if you are taking medications that interfere with blood clotting (such as Coumadin) or platelet function (such as aspirin, Motrin, ibuprofen, Aleve, and other NSAIDs). The wisest is to inform your doctor of any prescription or non-prescription medication you might be taking.
EUS is performed with sedation so you will not be able to return to work or to drive for the rest of the day. It also means that you will need someone to take you home as this is usually an out-patient procedure.
You will need to have an empty stomach that means no food or drink for 6 or more hours. In case of a rectal EUS you will need to take some enemas or laxatives. In either case, full instructions will be given to you.